abstract：:Reconstituted exametazime is inherently unstable due to the rapid oxidation of the small amount (7.6 micrograms) of stannous chloride present in the kit. A novel approach has been used to improve the shelf-life of reconstituted exametazime based on the premise that tin lost through oxidation should be replaced by furt...

journal_title：Nuclear medicine communications

authors： Solanki C,Li DJ,Wong A,Miles KA,Sampson CB

更新日期：1993-11-01 00:00:00

abstract：:Dynamic penile scintigraphy was performed using 99Tcm-labelled autologous erythrocytes in five normally potent volunteers and 22 patients with erectile dysfunction including 11 patients with psychogenic and 11 patients with vasculogenic impotence (four arteriogenic, three venogenic, three arteriogenic and venogenic, o...

journal_title：Nuclear medicine communications

authors： Siraj QH,Hilson AJ,Bomanji J,Ahmed M

更新日期：1993-11-01 00:00:00

abstract：:Twenty-nine patients (24 males, 5 females; aged 62.8 +/- 10.1 years) with noninsulin-dependent diabetes mellitus (NIDDM) without gallstones and impaired liver function were included in our study. The patients were categorized by blood sugar control and disease duration. Twelve normal controls (10 males, 2 females; age...

journal_title：Nuclear medicine communications

authors： Kao CH,Tsou CT,Wang SJ,Yeh SH

更新日期：1993-10-01 00:00:00

abstract：:Radiation doses to the family and general public from 131I therapy of outpatients were assessed for comparison with the 1990 International Commission on Radiation Protection (ICRP) dose limits. Doses to family members of such patients, measured by previous workers, were converted to show that on average 5.6 +/- 3.7 mi...

journal_title：Nuclear medicine communications

authors： Wasserman HJ,Klopper JF

更新日期：1993-09-01 00:00:00

abstract：:The criteria governing the in vivo use of monoclonal antibodies in humans are based upon a number of legal requirements with respect to radiation hygiene, pharmaceutical legislation, radiopharmaceutical legislation and regulations with respect to products arising from biotechnology. This in itself has led to a complic...

journal_title：Nuclear medicine communications

authors： Cox PH

更新日期：1993-08-01 00:00:00

abstract：:The aim of this study was to compare 99Tcm-teboroxime and 201T1 myocardial studies with particular regard to the classification of perfusion defects as reversible or fixed. Twenty patients with a history of previous myocardial infarction and suspected effort ischaemia underwent exercise 201T1 scintigraphy with early (...

journal_title：Nuclear medicine communications

authors： Bisi G,Sciagrà R,Santoro GM,Zerauschek F,Fazzini PF

更新日期：1993-07-01 00:00:00

abstract：:In order to evaluate the utility of positron emission tomography (PET) with 18F-labelled deoxyglucose (FDG) for detection of pancreatic cancer 15 patients with pancreatic masses shown by computed tomography were investigated. Static PET scans covering an axial field of view of 15 cm were obtained 45 min after intraven...

journal_title：Nuclear medicine communications

authors： Bares R,Klever P,Hellwig D,Hauptmann S,Fass J,Hambuechen U,Zopp L,Mueller B,Buell U,Schumpelick V

更新日期：1993-07-01 00:00:00

abstract：:A technique is described for the quantification of the three-dimensional distribution of 131I radiopharmaceuticals using single photon emission computed tomography (SPECT). A theoretical discussion of the problems of scatter and septal penetration in 131I SPECT is presented. The correction of these effects using the g...

journal_title：Nuclear medicine communications

authors： Fleming JS,Alaamer AA,Perring S

更新日期：1993-06-01 00:00:00

abstract：:The physical considerations of using dual isotope brain SPECT imaging to monitor blood flow changes during cognitive activation studies were investigated. These factors included field uniformity, spatial resolution and crosstalk. Serial dual isotope single photon emission computed tomographic (SPECT) studies of a test...

journal_title：Nuclear medicine communications

authors： Madsen MT,O'Leary DS,Andreasen NC,Kirchner PT

更新日期：1993-05-01 00:00:00

abstract：:This paper proposes the utilization of 225Ac for the alpha-radioimmunotherapy of cancer. The isotope decays with a radioactive half-life of 10 days into a cascade of short-lived alpha- and beta-emitting isotopes. In addition, when indicated by the pharmacokinetic requirements of particular clinical applications, 213Bi...

journal_title：Nuclear medicine communications

authors： Geerlings MW,Kaspersen FM,Apostolidis C,van der Hout R

更新日期：1993-02-01 00:00:00

abstract：:One hundred and twenty-eight patients had a stress test with sestamibi injection and a coronarography within 2 months of the sestamibi study. Sestamibi studies were reconstructed using Hanning 0.65 and Wiener 1.0 filters; the latter improved the results significantly (P < 0.05). Significant correlations were found bet...

journal_title：Nuclear medicine communications

authors： Solot G,Hermans J,Merlo P,Chaudron JM,Luwaert R,Cheron P,Bodart F,Beauduin M

更新日期：1993-01-01 00:00:00

abstract：:The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...

journal_title：Nuclear medicine communications

authors： Sciammarella MG,Fragasso G,Gerundini P,Maffioli L,Cappelletti A,Margonato A,Savi A,Chierchia S

更新日期：1992-12-01 00:00:00

abstract：:Should one correct for extrathyroidal neck radioactivity ('neck background') when interpreting perchlorate discharge test results? A new background correction method was developed using a linear probe. 123I produces photon peaks at two energy levels: 159 keV (gamma-rays) and 28 keV (X-rays), with an attenuation of 15 ...

journal_title：Nuclear medicine communications

authors： Arntzenius AB,van der Heide D,Meinders AE

更新日期：1992-11-01 00:00:00

abstract：:The ICRP has now recommended that the dose limit to the surface of the mother's abdomen during the declared term of pregnancy is reduced to 2 mSv. Direct measurements of the radiation dose to technologists carrying out a variety of imaging studies were made. The average dose ranged from 0.3 micro Sv for a liver scan t...

journal_title：Nuclear medicine communications

authors： Clarke EA,Thomson WH,Notghi A,Harding LK

更新日期：1992-11-01 00:00:00

abstract：:Changes in regional ejection fraction (rEF) of the interventricular septum following coronary artery bypass graft (CABG) surgery were examined using first-pass radionuclide ventriculography (RNVG) in patients without objective evidence of postoperative myocardial infarction (MI). One hundred and one patients had pre- ...

journal_title：Nuclear medicine communications

authors： Jacobson AF,Tow DE,Lapsley D,Khuri S

更新日期：1992-10-01 00:00:00

abstract：:Tumour uptake of the inert, neutral complex 67Ga-9N3 and the tumour:blood concentration ratio (1,4,7,triazacyclononane-1,4,7, triacetic acid) were measured in mice bearing xenografts of the human melanotic melanoma HX118. Between 1 and 4 h after the injection the tumour:blood ratio increased from 3.5 to 21 and the con...

journal_title：Nuclear medicine communications

authors： Harrison A,Walker CA,Pereira KA,Parker D,Royle L,Matthews RC,Craig AS

更新日期：1992-09-01 00:00:00

abstract：:Single photon emission computed tomography (SPECT) using N-isopropyl-p-(123I)iodoamphetamine (123I-IMP) and 99Tcm-hexamethylpropyleneamine oxime (99Tcm-HMPAO) was performed in 25 patients with different clinical stages of AIDS encephalopathy. The average interval between the two examinations was 7 days. In 15 of the 2...

journal_title：Nuclear medicine communications

authors： Pohl P,Riccabona G,Hilty E,Deisenhammer F,Rösslér H,Zangerle R,Gerstenbrand F

更新日期：1992-08-01 00:00:00

abstract：:Since the appearance of superficial tissue is often an unreliable indicator of deep tissue viability in cases of frostbite, radionuclide scintigraphy with 99Tcm-disodium oxidronate (HDP) was used to assess changes in tissue viability after experimental freezing and thawing of the rabbit ear. One shaved ear, left or ri...

journal_title：Nuclear medicine communications

authors： Junila J,Torniainen P,Kaarela O,Kairaluoma MI,Waris T

更新日期：1992-07-01 00:00:00

abstract：:A method is described for studying protein kinetics in pleural effusions in humans. In 15 patients with pleural effusions from a variety of causes, protein inflow was monitored by measuring the rate of appearance in the effusion of the plasma protein transferrin, radiolabelled in vivo by intravenous injection of 113In...

journal_title：Nuclear medicine communications

authors： Smith MJ,Joseph J,Flatman WD,Basran GS

更新日期：1992-06-01 00:00:00

abstract：:When preparing 99Tcm-exametazime, it is important to use sodium 99Tcm-pertechnetate that is less than 2 h old. The addition of sodium iodide (NaI) to 99Tcm-pertechnetate is known to extend this time to 6 h. This paper describes a technique for implementing this in routine practice. Sterile kits consisting of 440 micro...

journal_title：Nuclear medicine communications

authors： Millar AM

更新日期：1992-05-01 00:00:00

abstract：:A miniature, non-imaging caesium iodide nuclear probe optically coupled to a photodiode (the 'Cardioscint') has been developed which, in conjunction with a modified personal computer, is capable of continuous on-line monitoring of left ventricular function and ST-segment level at the bedside. The purpose of this study...

journal_title：Nuclear medicine communications

authors： Broadhurst P,Liu XJ,Cashman PM,Raftery EB,Lahiri A

更新日期：1992-05-01 00:00:00

abstract：:Providing information to patients and staff is an important part of the practice of nuclear medicine. To assist in improving the standard of communications, guidance has been prepared covering the content, style and presentation of letters and leaflets for patients and for medical and nursing staff. Examples are provi...

journal_title：Nuclear medicine communications

authors： Clarke SE,McKillop JH,Prescott MC,Williams ED

更新日期：1992-04-01 00:00:00

abstract：:Our study was aimed at determining the validity of 99Tcm-HMPAO single photon emission computed tomography (SPECT) in the localization of the epileptogenic focus by correlating this diagnostic method with other auxiliary investigations such as surface EEG and X-ray transmission computed tomography (CT). Twenty-eight pa...

journal_title：Nuclear medicine communications

authors： Verhoeff NP,Weinstein HC,Aldenkamp AP,Overweg J,Van Royen EA,Verbeeten B Jr

更新日期：1992-03-01 00:00:00

abstract：:This article discusses the problems facing nuclear medicine in the coming decade and outlines the areas in which new developments or expansion can be expected. The questions considered include legislative requirements, the need to educate the public and the medical profession on the strengths of nuclear medicine, appr...

journal_title：Nuclear medicine communications

authors： Ell PJ

更新日期：1992-02-01 00:00:00

abstract：:First-pass radionuclide angiography, for the evaluation of ventricular function during peak physiological stress, requires the use of a low-energy point source for correction of motion artifacts. A design for the construction of a refillable 125I point source is presented. ...

journal_title：Nuclear medicine communications

authors： Hirsch JI,Fuhs BE,Tatum JL,Tatum TG

更新日期：1992-01-01 00:00:00

abstract：:In an effort to develop new, clinically useful 99Tcm-diaminodithiol (99Tcm-DADT) complexes for the evaluation of regional cerebral perfusion, basic diaminodithiols (DADT-TM, DADT-HM and DADT-MHM) and three diaminodithiol ligands functionalized with p-iodophenethyl (DADT-IPE), N-ethyl-p-fluorophenethyl amine (DADT-EFPE...

journal_title：Nuclear medicine communications

authors： Shiba K,Mori H,Matsuda H,Hisada K

更新日期：1991-12-01 00:00:00

abstract：:Radionuclide limb blood flow measurements using 99Tcm-labelled human serum albumin and a gamma camera have been performed on normal volunteers and on patients with suspected or confirmed peripheral arterial disease. The normal range of flow was found to be 10.0-22.3 ml per 100 ml tissue per min. Flow in the symptomati...

journal_title：Nuclear medicine communications

authors： Parkin A,Robinson PJ,Martinez D,Wilkinson D,Kester RC

更新日期：1991-10-01 00:00:00

abstract：:A significant number of patients with primary hyperparathyroidism have negative preoperative 201Tl/99Tcm subtraction localization scans. In this study an attempt was made to improve scan localization by creating a period of relative hypocalcaemia and increased parathyroid hormone (PTH) secretion before scanning. Six p...

journal_title：Nuclear medicine communications

authors： Gallacher SJ,Fraser WD,Logue FC,Boyle IT,Gray HW,McKillop JH

更新日期：1991-09-01 00:00:00

abstract：:Infants or children undergoing nuclear medicine investigations may subsequently come into close contact with nurses or parents responsible for their care. In order to estimate the radiation dose to these individuals, and to formulate appropriate recommendations, dose rates were measured at distances of 0.1, 0.5 and 1....

journal_title：Nuclear medicine communications

authors： Mountford PJ,O'Doherty MJ,Harding LK,Thomson WH,Carter NJ,Bray D,Paul C,Batchelor S

更新日期：1991-08-01 00:00:00

abstract：:Patients infected with the human immunodeficiency virus (HIV) suffer from serious and life-threatening infections. These patients often present with pyrexia but without localizing signs. Despite its high sensitivity in identifying focal infection 67Ga citrate scintigraphy lacks specificity; lymphoma and solid tumours ...

journal_title：Nuclear medicine communications

authors： Buscombe JR,Miller RF,Lui D,Ell PJ

更新日期：1991-07-01 00:00:00

abstract：:The application of a Well-type germanium semiconductor detector creates new possibilities in erythrocyte survival studies. Using 51Cr, the effective dose equivalent in a standard procedure can be reduced from approximately 780 to 2 microSv. The properties of the detector, namely, high efficiency and high energy resolu...

journal_title：Nuclear medicine communications

authors： De Vries RA,Oldenburg SJ,Thelosen T,De Bruin M,Poortman J,Van de Wiel A

更新日期：1991-05-01 00:00:00

abstract：:The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. ...

journal_title：Nuclear medicine communications

authors： Britton KE,Mather SJ,Granowska M

更新日期：1991-04-01 00:00:00

abstract：:In this cross-sectional study, the relative importance of anthropometric factors and that of biological parameters on bone mineralization were evaluated and their practical implications inferred on the choice of the parameter to be used for the estimation of bone mineralization. A close relationship between anthropome...

journal_title：Nuclear medicine communications

authors： Rozenberg S,Ham H,Peretz A,Caufriez A,Bosson D,Robyn C

更新日期：1991-03-01 00:00:00

abstract：:The efficacy of wipe tests for assessing 99Tcm surface contamination was measured. Four types of surface were contaminated with four radiopharmaceuticals and wiped using four types of swab. The fraction of activity removed was measured by direct monitoring for each combination of surface, pharmaceutical and swab. The ...

journal_title：Nuclear medicine communications

authors： Scott LE,Gibson CJ

更新日期：1991-02-01 00:00:00

abstract：:First pass radionuclide angiocardiography (FPRNA) has gained increasing interest because of the development of new 99Tcm-labelled perfusion agents and of new 191Os/191Irm generator systems. The aim of the study was to evaluate the performance capacities of a small field of view single crystal digital gamma camera for ...

journal_title：Nuclear medicine communications

authors： Dobbeleir A,Franken PR,Ham HR,Brihaye C,Guillaume M,Knapp FF,Vandevivere J

更新日期：1991-01-01 00:00:00

abstract：:There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in th...

journal_title：Nuclear medicine communications

authors： Paul R,Kiiliäinen H,Tarssanen L,Vorne M

更新日期：1991-01-01 00:00:00

abstract：:A new radiopharmaceutical for hepatobiliary scanning, 99Tcm Iodida, which has significant advantages in patients with high bilirubinaemia, was used to assess biliary tract complications in 30 consecutive liver transplant patients. There was adequate hepatic extraction and excretion for diagnostic imaging even in patie...

journal_title：Nuclear medicine communications

authors： Lantsberg S,Lanchbury EE,Drolc ZA

更新日期：1990-11-01 00:00:00

abstract：:The blood flow in renal transplants can be represented by (1) a K/A ratio, the ratio of the slopes of the ascending part of the renal perfusion curve and the arterial curve, (2) a perfusion index, the ratio of a part of the area under the first-pass arterial curve and renal curve, and (3) a height ratio, the ratio of ...

journal_title：Nuclear medicine communications

authors： Groothedde RT,Koppejan LJ,Heidendal GK,Hasman A

更新日期：1990-11-01 00:00:00

abstract：:The purpose of this study was to validate different scintigraphic approaches for assessing acute myocardial infarctions. 201Tl, 99Tcm pyrophosphate (PPi) and combined 201Tl/99Tcm PPi tomograms were evaluated in 115 consecutive patients, in 85 of whom clinical examination revealed acute myocardial infarction. The overa...

journal_title：Nuclear medicine communications

authors： Krause T,Joseph A,Kutzner C,Kasper W,Schuemichen C,Just H,Moser E

更新日期：1990-09-01 00:00:00

abstract：:This study combines the pharmacologically-induced penile erection (PIPE) technique with radionuclide phallography (RNP) for the non-invasive study of penile haemodynamic changes during erection. Penile erections produced by the intracavernosal injections of two different vasoactive drugs, prostaglandin E1 (PGE1) and p...

journal_title：Nuclear medicine communications

authors： Siraj QH,Bomanji J,Akhtar MA,Rana MH,Sadiq M,Ahmed M

更新日期：1990-06-01 00:00:00